Gene Expression in Biopsies of Acute Rejection and Interstitial Fibrosis/Tubular Atrophy Reveals Highly Shared Mechanisms That Correlate With Worse Long-Term Outcomes

Interstitial fibrosis and tubular atrophy (IFTA) is found in approximately 25% of 1-year biopsies posttransplant. It is known that IFTA correlates with decreased graft survival when histological evidence of inflammation is present. Identifying the mechanistic etiology of IFTA is important to underst...

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Detalhes bibliográficos
Publicado no:Am J Transplant
Main Authors: Modena, B. D., Kurian, S. M., Gaber, L. W., Waalen, J., Su, A. I., Gelbart, T., Mondala, T. S., Head, S. R., Papp, S., Heilman, R., Friedewald, J. J., Flechner, S.M., Marsh, C. L., Sung, R. S., Shidban, H., Chan, L., Abecassis, M. M., Salomon, D. R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501990/
https://ncbi.nlm.nih.gov/pubmed/26990570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.13728
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