Quantification by Nano Liquid Chromatography-Parallel Reaction Monitoring-Mass Spectrometry of Human Apolipoprotein A-I, Apolipoprotein B, and Hemoglobin A1c in Dried Blood Spots

PURPOSE: Proteomic analysis of blood proteins in DBS is gaining attention as a possible replacement for measurements in plasma/serum collected by venipuncture. We aimed to develop and provisionally validate a nanoflow LC-PRM-MS method for clinical use. EXPERIMENTAL DESIGN: We used Skyline to develop...

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Bibliographic Details
Published in:Proteomics Clin Appl
Main Authors: Henderson, Clark M., Bollinger, James G., Becker, Jessica O., Wallace, Jennifer M., Laha, Thomas J., MacCoss, Michael J., Hoofnagle, Andrew N.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501987/
https://ncbi.nlm.nih.gov/pubmed/28112871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prca.201600103
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