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Whole transcriptome profiling of the human hippocampus suggests an involvement of the KIBRA rs17070145 polymorphism in differential activation of the MAPK signaling pathway

The rs17070145-T variant of the WWC1 gene, coding for the KIBRA protein, has been associated with both increased episodic memory performance and lowered risk for late onset Alzheimer’s disease, although the mechanism behind this protective effect has not been completely elucidated. To achieve a bett...

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Publicat a:Hippocampus
Autors principals: Piras, IS, Krate, J, Schrauwen, I, Corneveaux, JJ, Serrano, GE, Sue, L, Beach, TG, Huentelman, MJ
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501956/
https://ncbi.nlm.nih.gov/pubmed/28380666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.22731
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