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Regulation of early growth response 2 expression by secreted frizzled related protein 1
BACKGROUND: Secreted frizzled-related protein 1 (SFRP1) expression is down-regulated in a multitude of cancers, including breast cancer. Loss of Sfrp1 also exacerbates weight gain as well as inflammation. Additionally, loss of SFRP1 enhances TGF-β signaling and the downstream MAPK pathway. TGF-β has...
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| Izdano u: | BMC Cancer |
|---|---|
| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501954/ https://ncbi.nlm.nih.gov/pubmed/28687085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3426-y |
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