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Fluvoxamine stimulates oligodendrogenesis of cultured neural stem cells and attenuates inflammation and demyelination in an animal model of multiple sclerosis

Multiple Sclerosis (MS) require medications controlling severity of the pathology and depression, affecting more than half of the patients. In this study, the effect of antidepressant drug fluvoxamine, a selective serotonin reuptake inhibitor, was investigated in vitro and in vivo. Nanomolar concent...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ghareghani, Majid, Zibara, Kazem, Sadeghi, Heibatollah, Dokoohaki, Shima, Sadeghi, Hossein, Aryanpour, Roya, Ghanbari, Amir
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501834/
https://ncbi.nlm.nih.gov/pubmed/28687730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04968-z
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