Genetic variants of TRAF6 modulate peritoneal immunity and the risk of spontaneous bacterial peritonitis in cirrhosis: A combined prospective-retrospective study

Alterations of the innate immunity contribute to the development of spontaneous bacterial peritonitis (SBP) in liver cirrhosis. Given its role in immune signaling, antimicrobial function, and macrophage differentiation, we hypothesized that genetic polymorphisms of TRAF6 modulate the risk of SBP. Th...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mai, Martina, Stengel, Sven, Al-Herwi, Eihab, Peter, Jack, Schmidt, Caroline, Rubio, Ignacio, Stallmach, Andreas, Bruns, Tony
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501819/
https://ncbi.nlm.nih.gov/pubmed/28687809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04895-z
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