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Recruited monocytes and Th2 cytokine signaling promote lung regeneration following pneumonectomy
To investigate the role of immune cells in lung regeneration, we used a unilateral pneumonectomy model that promotes the formation of new alveoli in the remaining lobes. Immunofluorescence and single cell RNA- sequencing found CD115+ and CCR2+ monocytes and M2-like macrophages accumulating in the lu...
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| Udgivet i: | Cell Stem Cell |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501755/ https://ncbi.nlm.nih.gov/pubmed/28506464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2017.03.024 |
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