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Correlation of the structure of the transmembrane domain of the neu oncogene-encoded p185 protein with its function.

The human homologue of the neu oncogene is frequently found in human tumors. Certain amino acid substitutions at position 664 in the transmembrane domain of the neu oncogene-encoded p185 protein product are known to cause malignant transformation of cells. Using conformational energy analysis based...

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Main Authors: Brandt-Rauf, P W, Rackovsky, S, Pincus, M R
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC55017/
https://ncbi.nlm.nih.gov/pubmed/1978329
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