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A human endogenous retrovirus-derived gene that can contribute to oncogenesis by activating the ERK pathway and inducing migration and invasion

Endogenous retroviruses are cellular genes of retroviral origin captured by their host during the course of evolution and represent around 8% of the human genome. Although most are defective and transcriptionally silenced, some are still able to generate retroviral-like particles and proteins. Among...

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Библиографические подробности
Опубликовано в: :PLoS Pathog
Главные авторы: Lemaître, Cécile, Tsang, Jhen, Bireau, Caroline, Heidmann, Thierry, Dewannieux, Marie
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501692/
https://ncbi.nlm.nih.gov/pubmed/28651004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006451
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