Synthesis, construction, and evaluation of self-assembled nano-bacitracin A as an efficient antibacterial agent in vitro and in vivo

Bacitracin A (BA) is an excellent polypeptide antibiotic that is active against gram-positive bacteria without triggering multidrug resistance. However, BA is inactive against gram-negative bacteria because of its inability to cross the outer membrane of these cells, and it has strong nephrotoxicity...

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Библиографические подробности
Опубликовано в: :Int J Nanomedicine
Главные авторы: Hong, Wei, Gao, Xiang, Qiu, Peng, Yang, Jie, Qiao, Mingxi, Shi, Hong, Zhang, Dexian, Tian, Chunlian, Niu, Shengli, Liu, Mingchun
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2017
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501637/
https://ncbi.nlm.nih.gov/pubmed/28721045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S136998
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