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Flow velocity-driven differentiation of human mesenchymal stromal cells in silk fibroin scaffolds: A combined experimental and computational approach

Mechanical loading plays a major role in bone remodeling and fracture healing. Mimicking the concept of mechanical loading of bone has been widely studied in bone tissue engineering by perfusion cultures. Nevertheless, there is still debate regarding the in-vitro mechanical stimulation regime. This...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Vetsch, Jolanda Rita, Betts, Duncan Colin, Müller, Ralph, Hofmann, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501602/
https://ncbi.nlm.nih.gov/pubmed/28686698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180781
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