STAT3 balances myocyte hypertrophy vis-à-vis autophagy in response to Angiotensin II by modulating the AMPKα/mTOR axis

Signal transducers and activators of transcription 3 (STAT3) is known to participate in various cardiovascular signal transduction pathways, including those responsible for cardiac hypertrophy and cytoprotection. However, the role of STAT3 signaling in cardiomyocyte autophagy remains unclear. We tes...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Chen, Lei, Zhao, Lin, Samanta, Anweshan, Mahmoudi, Seyed Morteza, Buehler, Tanner, Cantilena, Amy, Vincent, Robert J., Girgis, Magdy, Breeden, Joshua, Asante, Samuel, Xuan, Yu-Ting, Dawn, Buddhadeb
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501431/
https://ncbi.nlm.nih.gov/pubmed/28686615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179835
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