Defined Engineered Human Myocardium with Advanced Maturation for Applications in Heart Failure Modelling and Repair

BACKGROUND: Advancing structural and functional maturation of stem cell-derived cardiomyocytes remains a key challenge for applications in disease modelling, drug screening, and heart repair. Here, we sought to advance cardiomyocyte maturation in engineered human myocardium (EHM) towards an adult ph...

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Publicado en:Circulation
Main Authors: Tiburcy, Malte, Hudson, James E., Balfanz, Paul, Schlick, Susanne, Meyer, Tim, Liao, Mei-Ling Chang, Levent, Elif, Raad, Farah, Zeidler, Sebastian, Wingender, Edgar, Riegler, Johannes, Wang, Mouer, Gold, Joseph D., Kehat, Izhak, Wettwer, Erich, Ravens, Ursula, Dierickx, Pieterjan, van Laake, Linda W., Goumans, Marie Jose, Khadjeh, Sara, Toischer, Karl, Hasenfuss, Gerd, Couture, Larry A., Unger, Andreas, Linke, Wolfgang A., Araki, Toshiyuki, Neel, Benjamin, Keller, Gordon, Gepstein, Lior, Wu, Joseph C., Zimmermann, Wolfram-Hubertus
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501412/
https://ncbi.nlm.nih.gov/pubmed/28167635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.116.024145
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