Management of flu-like syndrome with cetirizine in patients with relapsing-remitting multiple sclerosis during therapy with interferon beta: Results of a randomized, cross-over, placebo-controlled pilot study

BACKGROUND: Flu-like syndrome (FLS) is a common adverse event experienced by patients with relapsing-remitting multiple sclerosis (RRMS) treated with interferon beta (IFNβ). FLS can lead to poor treatment adherence and early IFNβ discontinuation. The involvement of interleukin-6 (IL-6) in the occurr...

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Bibliographic Details
Published in:PLoS One
Main Authors: Landi, Doriana, Albanese, Maria, Buttari, Fabio, Monteleone, Fabrizia, Boffa, Laura, Rossi, Silvia, Motta, Caterina, Puma, Elisa, Centonze, Diego
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501388/
https://ncbi.nlm.nih.gov/pubmed/28686675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165415
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