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Molecular mapping of the mouse db mutation.

Diabetes (db) is an autosomal recessive mutation located in the midportion of mouse chromosome 4 that results in profound obesity with hyperphagia, increased metabolic efficiency, and insulin resistance. To clone this gene and generate a molecular map of the region around this mutation, two genetic...

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Autors principals: Bahary, N, Leibel, R L, Joseph, L, Friedman, J M
Format: Artigo
Idioma:Inglês
Publicat: 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC55013/
https://ncbi.nlm.nih.gov/pubmed/1978328
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