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Quantification of lactate dehydrogenase for cell viability testing using cell lines and primary cultured astrocytes
Drug discovery heavily relies on cell viability studies to assess the potential toxicity of drug candidates. L-Lactate dehydrogenase (LDH) is a cytoplasmic enzyme that catalyzes the concomitant interconversions of pyruvate to L-lactate and NADH to NAD(+) during glycolysis, and the reverse reactions...
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Publicado no: | Curr Protoc Toxicol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501254/ https://ncbi.nlm.nih.gov/pubmed/28463416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cptx.21 |
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