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Quantification of lactate dehydrogenase for cell viability testing using cell lines and primary cultured astrocytes

Drug discovery heavily relies on cell viability studies to assess the potential toxicity of drug candidates. L-Lactate dehydrogenase (LDH) is a cytoplasmic enzyme that catalyzes the concomitant interconversions of pyruvate to L-lactate and NADH to NAD(+) during glycolysis, and the reverse reactions...

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Podrobná bibliografie
Vydáno v:Curr Protoc Toxicol
Hlavní autoři: Kaja, Simon, Payne, Andrew J., Naumchuk, Yuliya, Koulen, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501254/
https://ncbi.nlm.nih.gov/pubmed/28463416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cptx.21
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