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The heme-regulatory motif of nuclear receptor Rev-erbβ is a key mediator of heme and redox signaling in circadian rhythm maintenance and metabolism

Rev-erbβ is a heme-responsive transcription factor that regulates genes involved in circadian rhythm maintenance and metabolism, effectively bridging these critical cellular processes. Heme binding to Rev-erbβ indirectly facilitates its interaction with the nuclear receptor co-repressor (NCoR1), res...

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Vydáno v:J Biol Chem
Hlavní autoři: Carter, Eric L., Ramirez, Yanil, Ragsdale, Stephen W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500795/
https://ncbi.nlm.nih.gov/pubmed/28500133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.783118
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