Quantitative microspectroscopic imaging reveals viral and cellular RNA helicase interactions in live cells

Human cells detect RNA viruses through a set of helicases called RIG-I-like receptors (RLRs) that initiate the interferon response via a mitochondrial signaling complex. Many RNA viruses also encode helicases, which are sometimes covalently linked to proteases that cleave signaling proteins. One unr...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Corby, M. J., Stoneman, Michael R., Biener, Gabriel, Paprocki, Joel D., Kolli, Rajesh, Raicu, Valerica, Frick, David N.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500786/
https://ncbi.nlm.nih.gov/pubmed/28483922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.777045
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