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Adiponectin Upregulates Filaggrin Expression via SIRT1-Mediated Signaling in Human Normal Keratinocytes
BACKGROUND: Filaggrin (FLG) is the major component of the epidermal granular layer and binds to and condenses the keratin cytoskeleton. FLG thus contributes to cell compaction and serves as a natural moisturizing factor by promoting unfolding and degradation into hygroscopic amino acids. Loss or dow...
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| Publicat a: | Ann Dermatol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Korean Dermatological Association; The Korean Society for Investigative Dermatology
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5500704/ https://ncbi.nlm.nih.gov/pubmed/28761287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5021/ad.2017.29.4.407 |
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