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Evaluating the influence of mechanical stress on anticancer treatments through a multiphase porous media model

Drug resistance is one of the leading causes of poor therapy outcomes in cancer. As several chemotherapeutics are designed to target rapidly dividing cells, the presence of a low-proliferating cell population contributes significantly to treatment resistance. Interestingly, recent studies have shown...

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Publicat a:J Theor Biol
Autors principals: Mascheroni, Pietro, Boso, Daniela, Preziosi, Luigi, Schrefler, Bernhard A.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500690/
https://ncbi.nlm.nih.gov/pubmed/28392183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2017.03.027
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