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Detection of EGFR mutation in plasma using multiplex allele-specific PCR (MAS-PCR) and surface enhanced Raman spectroscopy

In this study, surface enhanced Raman spectroscopy (SERS) in combination with multiplexed polymerase chain reaction (PCR) was utilized to detect mutations of exons 19 and 21 of the epidermal growth factor receptor (EGFR) gene. Through the use of multiplexed PCR, the two mutation types were amplified...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Xiaozhou, Yang, Tianyue, Li, Caesar Siqi, Wang, Deli, Song, Youtao, Jin, Lili
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500569/
https://ncbi.nlm.nih.gov/pubmed/28684733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05050-4
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