Tumoral expression of drug and xenobiotic metabolizing enzymes in breast cancer patients of different ethnicities with implications to personalized medicine

Drug and xenobiotic metabolizing enzymes (DXME) play important roles in drug responses and carcinogenesis. Recent studies have found that expression of DXME in cancer cells significantly affects drug clearance and the onset of drug resistance. In this study we compared the expression of DXME in brea...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Yan, Steppi, Albert, Zhou, Yidong, Mao, Feng, Miller, Philip Craig, He, Max M., Zhao, Tingting, Sun, Qiang, Zhang, Jinfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500564/
https://ncbi.nlm.nih.gov/pubmed/28684774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04250-2
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