Cell and small animal models for phenotypic drug discovery

The phenotype-based drug discovery (PDD) approach is re-emerging as an alternative platform for drug discovery. This review provides an overview of the various model systems and technical advances in imaging and image analyses that strengthen the PDD platform. In PDD screens, compounds of therapeuti...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Szabo, Mihaly, Svensson Akusjärvi, Sara, Saxena, Ankur, Liu, Jianping, Chandrasekar, Gayathri, Kitambi, Satish S
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2017
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500539/
https://ncbi.nlm.nih.gov/pubmed/28721015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S129447
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