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Thrombin-induced cytoskeleton dynamics in spread human platelets observed with fast scanning ion conductance microscopy

Platelets are small anucleate blood cells involved in haemostasis. Platelet activation, caused by agonists such as thrombin or by contact with the extracellular matrix, leads to platelet adhesion, aggregation, and coagulation. Activated platelets undergo shape changes, adhere, and spread at the site...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Seifert, Jan, Rheinlaender, Johannes, Lang, Florian, Gawaz, Meinrad, Schäffer, Tilman E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500533/
https://ncbi.nlm.nih.gov/pubmed/28684746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04999-6
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