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Mechanistic action of weak acid drugs on biofilms

Selective permeability of a biofilm matrix to some drugs has resulted in the development of drug tolerant bacteria. Here we studied the efficacy of a weak organic acid drug, N-acetyl-L-cysteine (NAC), on the eradication of biofilms formed by the mucoid strain of Pseudomonas aeruginosa and investigat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kundukad, Binu, Schussman, Megan, Yang, Kaiyuan, Seviour, Thomas, Yang, Liang, Rice, Scott A., Kjelleberg, Staffan, Doyle, Patrick S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500524/
https://ncbi.nlm.nih.gov/pubmed/28684849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05178-3
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