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Comparison of gefitinib as first- and second-line therapy for advanced lung adenocarcinoma patients with positive exon 21 or 19 del epidermal growth factor receptor mutation

OBJECTIVES: Gefitinib, a tyrosine kinase inhibitor (TKI) targeting epidermal growth factor receptor (EGFR), shows excellent clinical benefit in treating advanced non-small-cell lung cancer (NSCLC). The aim of this study was to compare the efficacy and toxicity of gefitinib as first-line therapy and...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Patel, Nishant, Wu, Pingping, Zhang, Haijun
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500485/
https://ncbi.nlm.nih.gov/pubmed/28721096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S138643
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