The Src family kinase inhibitor dasatinib delays pain-related behaviour and conserves bone in a rat model of cancer-induced bone pain

Pain is a severe and debilitating complication of metastatic bone cancer. Current analgesics do not provide sufficient pain relief for all patients, creating a great need for new treatment options. The Src kinase, a non-receptor protein tyrosine kinase, is implicated in processes involved in cancer-...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Appel, Camilla Kristine, Gallego-Pedersen, Simone, Andersen, Line, Blancheflor Kristensen, Sophie, Ding, Ming, Falk, Sarah, Sayilekshmy, Manasi, Gabel-Jensen, Charlotte, Heegaard, Anne-Marie
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500481/
https://ncbi.nlm.nih.gov/pubmed/28684771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05029-1
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