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Silibinin Treatment Inhibits the Growth of Hedgehog Inhibitor Resistant Basal Cell Carcinoma Cells via Targeting EGFR-MAPK-Akt and Hedgehog Signaling()

Basal cell carcinoma (BCC) is the most common skin malignancy. Deregulated hedgehog signaling plays a central role in BCC development; therefore hedgehog inhibitors have been approved to treat locally advanced or metastatic BCC. However, the development of resistance to hedgehog inhibitors is the ma...

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Detalhes bibliográficos
Publicado no:Photochem Photobiol
Main Authors: Dheeraj, Arpit, Rigby, Cynthia M., O’Bryant, Cindy L., Agarwal, Chapla, Singh, Rana P., Deep, Gagan, Agarwal, Rajesh
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500419/
https://ncbi.nlm.nih.gov/pubmed/28120452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/php.12727
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