Helicobacter pylori gene silencing in vivo demonstrates urease is essential for chronic infection

Helicobacter pylori infection causes chronic active gastritis that after many years of infection can develop into peptic ulceration or gastric adenocarcinoma. The bacterium is highly adapted to surviving in the gastric environment and a key adaptation is the virulence factor urease. Although widely...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Debowski, Aleksandra W., Walton, Senta M., Chua, Eng-Guan, Tay, Alfred Chin-Yen, Liao, Tingting, Lamichhane, Binit, Himbeck, Robyn, Stubbs, Keith A., Marshall, Barry J., Fulurija, Alma, Benghezal, Mohammed
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500380/
https://ncbi.nlm.nih.gov/pubmed/28644872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006464
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