Enterolactone induces G(1)-phase cell cycle arrest in non-small cell lung cancer cells by down-regulating cyclins and cyclin-dependent kinases

Flaxseed is a rich source of the plant lignan secoisolariciresinol diglucoside (SDG) which is metabolized into mammalian lignans enterodiol (ED) and enterolactone (EL) in the digestive tract. The anti-cancer properties of these lignans have been demonstrated for various cancer types, but have not be...

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Bibliographic Details
Published in:Nutr Cancer
Main Authors: Chikara, Shireen, Lindsey, Kaitlin, Dhillon, Harsharan, Mamidi, Sujan, Kittilson, Jeffrey, Christofidou-Solomidou, Melpo, Reindl, Katie M.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500210/
https://ncbi.nlm.nih.gov/pubmed/28323486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01635581.2017.1296169
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