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Residues in the Nucleosome Acidic Patch Regulate Histone Occupancy and Are Important for FACT Binding in Saccharomyces cerevisiae

The essential histone chaperone FACT plays a critical role in DNA replication, repair, and transcription, primarily by binding to histone H2A-H2B dimers and regulating their assembly into nucleosomes. While FACT histone chaperone activity has been extensively studied, the exact nature of the H2A and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genetics
Prif Awduron: Hodges, Amelia J., Gloss, Lisa M., Wyrick, John J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Genetics Society of America 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500134/
https://ncbi.nlm.nih.gov/pubmed/28468903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.201939
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