RNA stores tau reversibly in complex coacervates

Nonmembrane-bound organelles that behave like liquid droplets are widespread among eukaryotic cells. Their dysregulation appears to be a critical step in several neurodegenerative conditions. Here, we report that tau protein, the primary constituent of Alzheimer neurofibrillary tangles, can form liq...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Zhang, Xuemei, Lin, Yanxian, Eschmann, Neil A., Zhou, Hongjun, Rauch, Jennifer N., Hernandez, Israel, Guzman, Elmer, Kosik, Kenneth S., Han, Songi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500003/
https://ncbi.nlm.nih.gov/pubmed/28683104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2002183
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