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Consequences of a tight squeeze: Nuclear envelope rupture and repair
Cell migration through tight spaces can induce substantial deformations of the nucleus and cause nuclear envelope (NE) rupture, resulting in uncontrolled exchange of nuclear and cytosolic proteins. These events can cause DNA damage and, in severe cases, nuclear fragmentation, challenging the integri...
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| Publicado no: | Nucleus |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5499899/ https://ncbi.nlm.nih.gov/pubmed/28287898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2017.1292191 |
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