Adverse renal effects of anaplastic lymphoma kinase inhibitors and the response to alectinib of an ALK+ lung cancer patient with renal dysfunction

A 62-year-old female patient with renal dysfunction and pulmonary adenocarcinoma developed postoperative recurrence and received carboplatin/pemetrexed and maintenance pemetrexed. As an anaplastic lymphoma kinase (ALK) gene translocation was identified, the therapy was changed to crizotinib. However...

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Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Shimada, Midori, Fukuda, Minoru, Fukuda, Masaaki, Kitazaki, Takeshi, Hashiguchi, Kohji, Ikeda, Takaya, Yamaguchi, Hiroyuki, Nakatomi, Katsumi, Ashizawa, Kazuto, Mukae, Hiroshi
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2017
Subjects:
Case Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499859/
https://ncbi.nlm.nih.gov/pubmed/28721071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S136837
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