EMAP-II sensitize U87MG and glioma stem-like cells to temozolomide via induction of autophagy-mediated cell death and G2/M arrest

Despite the fact that temozolomide (TMZ) has been widely accepted as the key chemotherapeutic agent to prolong the survival of patients with glioblastoma, failure and recurrence cases can still be observed in clinics. Glioma stem-like cells (GSCs) are thought to be responsible for the drug resistanc...

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Vydáno v:Cell Cycle
Hlavní autoři: Yu, Qi, Liu, Libo, Wang, Ping, Yao, Yilong, Xue, Yixue, Liu, Yunhui
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499844/
https://ncbi.nlm.nih.gov/pubmed/28436750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1315492
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