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Hypoxia favors the generation of human plasma cells

Plasma cells (PCs) generation occurs in hypoxic conditions in vivo, whereas the relevance of O(2) pressure in PC differentiation remains unknown. Using our in vitro PC differentiation model, we investigated the role of hypoxia in PC generation. Hypoxia increases the generation of plasmablasts (PBs)...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Schoenhals, Matthieu, Jourdan, Michel, Bruyer, Angélique, Kassambara, Alboukadel, Klein, Bernard, Moreaux, Jérôme
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499840/
https://ncbi.nlm.nih.gov/pubmed/28463531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1317408
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