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Clinical use of lenvatinib in combination with everolimus for the treatment of advanced renal cell carcinoma

INTRODUCTION: Renal cell carcinoma (RCC) represents 2%–3% of all cancers in adults, and its pathogenesis is mainly related to altered cellular response to hypoxia. Lenvatinib, a novel multitarget tyrosine kinase inhibitor (TKI), represents a therapeutic option, in combination with mammalian target o...

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Dettagli Bibliografici
Pubblicato in:Ther Clin Risk Manag
Autori principali: Leonetti, Alessandro, Leonardi, Francesco, Bersanelli, Melissa, Buti, Sebastiano
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499780/
https://ncbi.nlm.nih.gov/pubmed/28721060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TCRM.S126910
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