Galangin Activates the ERK/AKT-Driven Nrf2 Signaling Pathway to Increase the Level of Reduced Glutathione in Human Keratinocytes

Previously, we demonstrated that galangin (3,5,7-trihydroxyflavone) protects human keratinocytes against ultraviolet B (UVB)-induced oxidative damage. In this study, we investigated the effect of galangin on induction of antioxidant enzymes involved in synthesis of reduced glutathione (GSH), and inv...

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Vydáno v:Biomol Ther (Seoul)
Hlavní autoři: Hewage, Susara Ruwan Kumara Madduma, Piao, Mei Jing, Kang, Kyoung Ah, Ryu, Yea Seong, Fernando, Pattage Madushan Dilhara Jayatissa, Oh, Min Chang, Park, Jeong Eon, Shilnikova, Kristina, Moon, Yu Jin, Shin, Dae O, Hyun, Jin Won
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Society of Applied Pharmacology 2017
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499622/
https://ncbi.nlm.nih.gov/pubmed/27829272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2016.112
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