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Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation
The catalytic activity of human cytidine deaminase APOBEC3B (A3B) has been correlated with kataegic mutational patterns within multiple cancer types. The molecular basis of how the N-terminal non-catalytic CD1 regulates the catalytic activity and consequently, biological function of A3B remains rela...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5499559/ https://ncbi.nlm.nih.gov/pubmed/28575276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx362 |
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