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eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequences

eIF5A is an essential protein involved in protein synthesis, cell proliferation and animal development. High eIF5A expression is observed in many tumor types and has been linked to cancer metastasis. Recent studies have shown that eIF5A facilitates the translation elongation of stretches of consecut...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Pelechano, Vicent, Alepuz, Paula
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499558/
https://ncbi.nlm.nih.gov/pubmed/28549188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx479
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