A salt-sensing kinase in T lymphocytes, SGK1, drives hypertension and hypertensive end-organ damage

We previously showed that angiotensin II (Ang II) increases T cell production of IL-17A, and that mice deficient in IL-17A have blunted hypertension and attenuated renal and vascular dysfunction. It was recently shown that salt enhances IL-17A production from CD4(+) T cells via a serum- and glucocor...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Norlander, Allison E., Saleh, Mohamed A., Pandey, Arvind K., Itani, Hana A., Wu, Jing, Xiao, Liang, Kang, Jooeun, Dale, Bethany L., Goleva, Slavina B., Laroumanie, Fanny, Du, Liping, Harrison, David G., Madhur, Meena S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499362/
https://ncbi.nlm.nih.gov/pubmed/28679951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92801
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