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RNAi-Mediated Reverse Genetic Screen Identified Drosophila Chaperones Regulating Eye and Neuromuscular Junction Morphology

Accumulation of toxic proteins in neurons has been linked with the onset of neurodegenerative diseases, which in many cases are characterized by altered neuronal function and synapse loss. Molecular chaperones help protein folding and the resolubilization of unfolded proteins, thereby reducing the p...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Raut, Sandeep, Mallik, Bhagaban, Parichha, Arpan, Amrutha, Valsakumar, Sahi, Chandan, Kumar, Vimlesh
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499113/
https://ncbi.nlm.nih.gov/pubmed/28500055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.041632
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