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RNAi-Mediated Reverse Genetic Screen Identified Drosophila Chaperones Regulating Eye and Neuromuscular Junction Morphology

Accumulation of toxic proteins in neurons has been linked with the onset of neurodegenerative diseases, which in many cases are characterized by altered neuronal function and synapse loss. Molecular chaperones help protein folding and the resolubilization of unfolded proteins, thereby reducing the p...

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Detalles Bibliográficos
Publicado en:G3 (Bethesda)
Main Authors: Raut, Sandeep, Mallik, Bhagaban, Parichha, Arpan, Amrutha, Valsakumar, Sahi, Chandan, Kumar, Vimlesh
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499113/
https://ncbi.nlm.nih.gov/pubmed/28500055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.041632
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