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Polyplex Evolution: Understanding Biology, Optimizing Performance

Polyethylenimine (PEI) is a gold standard polycationic transfectant. However, the highly efficient transfecting activity of PEI and many of its derivatives is accompanied by serious cytotoxic complications and safety concerns at innate immune levels, which impedes the development of therapeutic poly...

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Bibliografske podrobnosti
izdano v:Mol Ther
Main Authors: Hall, Arnaldur, Lächelt, Ulrich, Bartek, Jiri, Wagner, Ernst, Moghimi, Seyed Moein
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498806/
https://ncbi.nlm.nih.gov/pubmed/28274797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.01.024
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