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Polyplex Evolution: Understanding Biology, Optimizing Performance

Polyethylenimine (PEI) is a gold standard polycationic transfectant. However, the highly efficient transfecting activity of PEI and many of its derivatives is accompanied by serious cytotoxic complications and safety concerns at innate immune levels, which impedes the development of therapeutic poly...

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Библиографические подробности
Опубликовано в: :Mol Ther
Главные авторы: Hall, Arnaldur, Lächelt, Ulrich, Bartek, Jiri, Wagner, Ernst, Moghimi, Seyed Moein
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Gene & Cell Therapy 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498806/
https://ncbi.nlm.nih.gov/pubmed/28274797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.01.024
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