Molecular docking based screening of Listeriolysin-O for improved inhibitors

Listeriolysine-O (LLO) is a 50KDa protein responsible for Listeria monocytogenes pathogenicity. The structure of LLO (PDB ID: 4CDB) with domains D1 to D4 is known. Therefore, it is of interest to identify conserved regions among LLO variants for destabilizing oligomerization (50 mer complex) of its...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bioinformation
Prif Awduron: Ghafari, Sara, Komeilian, Matin, Hashemi, Mohaddese sadat, Oushani, Sareh, Rigi, Garshasb, Rashidieh, Behnam, Yarahmadi, Kamran, Khoddam, Fatemeh
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Biomedical Informatics 2017
Pynciau:
Hypothesis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498783/
https://ncbi.nlm.nih.gov/pubmed/28690383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630013160
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