Identification of Protective B-Cell Epitopes within the Novel Malaria Vaccine Candidate Plasmodium falciparum Schizont Egress Antigen 1

Naturally acquired antibodies to Plasmodium falciparum schizont egress antigen 1 (PfSEA-1A) are associated with protection against severe malaria in children. Vaccination of mice with SEA-1A from Plasmodium berghei (PbSEA-1A) decreases parasitemia and prolongs survival following P. berghei ANKA chal...

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Udgivet i:Clin Vaccine Immunol
Main Authors: Nixon, Christina E., Park, Sangshin, Pond-Tor, Sunthorn, Raj, Dipak, Lambert, Lynn E., Orr-Gonzalez, Sachy, Barnafo, Emma K., Rausch, Kelly M., Friedman, Jennifer F., Fried, Michal, Duffy, Patrick E., Kurtis, Jonathan D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498721/
https://ncbi.nlm.nih.gov/pubmed/28468980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00068-17
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