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High-dose fluconazole in combination with amphotericin B is more efficient than monotherapy in murine model of cryptococcosis

Cryptococcus spp., the causative agents of cryptococcosis, are responsible for deaths of hundreds of thousands of people every year worldwide. The drawbacks of available therapeutic options are aggravated by the increased resistance of yeast to the drugs, resulting in inefficient therapy. Also, the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Santos, Julliana Ribeiro Alves, Ribeiro, Noelly Queiroz, Bastos, Rafael Wesley, Holanda, Rodrigo Assunção, Silva, Letícia Chagas, Queiroz, Estela Rezende, Santos, Daniel Assis
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498649/
https://ncbi.nlm.nih.gov/pubmed/28680034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04588-7
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