Functional analysis of protein N-myristoylation: metabolic labeling studies using three oxygen-substituted analogs of myristic acid and cultured mammalian cells provide evidence for protein-sequence-specific incorporation and analog-specific redistribution.

Covalent attachment of myristic acid (C14:0) to the NH2-terminal glycine residue of a number of cellular, viral, and oncogene-encoded proteins is essential for full expression of their biological function. Substitution of oxygen for methylene groups in this fatty acid does not produce a significant...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Johnson, D R, Cox, A D, Solski, P A, Devadas, B, Adams, S P, Leimgruber, R M, Heuckeroth, R O, Buss, J E, Gordon, J I
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1990
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC54986/
https://ncbi.nlm.nih.gov/pubmed/2236060
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