Identification of HCV Resistant Variants against Direct Acting Antivirals in Plasma and Liver of Treatment Naïve Patients

Current standard-of-care treatment of chronically infected hepatitis C virus (HCV) patients involves direct-acting antivirals (DAA). However, concerns exist regarding the emergence of drug -resistant variants and subsequent treatment failure. In this study, we investigate potential natural drug-resi...

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Vydáno v:Sci Rep
Hlavní autoři: Raj, V. Stalin, Hundie, Gadissa Bedada, Schürch, Anita C., Smits, Saskia L., Pas, Suzan D., Le Pogam, Sophie, Janssen, Harry L. A., de Knegt, Rob J., Osterhaus, Albert D. M. E., Najera, Isabel, Boucher, Charles A., Haagmans, Bart L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498547/
https://ncbi.nlm.nih.gov/pubmed/28680115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04931-y
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