Generation of novel patient-derived CIC-DUX4 sarcoma xenografts and cell lines

CIC-DUX4 sarcoma (CDS) is a group of rare, mesenchymal, small round cell tumours that harbour the unique CIC-DUX4 translocation, which causes aberrant gene expression. CDS exhibits an aggressive course and poor clinical outcome, thus novel therapeutic approaches are needed for CDS treatment. Althoug...

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Publicat a:Sci Rep
Autors principals: Oyama, Rieko, Takahashi, Mami, Yoshida, Akihiko, Sakumoto, Marimu, Takai, Yoko, Kito, Fusako, Shiozawa, Kumiko, Qiao, Zhiwei, Arai, Yasuhito, Shibata, Tatsuhiro, Araki, Yoshihiro, Endo, Makoto, Kawai, Akira, Kondo, Tadashi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498486/
https://ncbi.nlm.nih.gov/pubmed/28680140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04967-0
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