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Detection of Emodin Derived Glutathione Adduct in Normal Rats Administered with Large Dosage of Polygoni Multiflori Radix

Polygoni Multiflori Radix (PMR) has been commonly used as a tonic in China for centuries. PMR-associated hepatotoxicity has been drawing increasingly more attention in recent years in parallel with its wide utilization. Anthraquinones (AQs) are recognized as the main hepatotoxic components in PMR. H...

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Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Jiang, Li-Long, Zhao, Dong-Sheng, Fan, Ya-Xi, Yu, Qiong, Li, Ping, Li, Hui-Jun
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498464/
https://ncbi.nlm.nih.gov/pubmed/28729838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00446
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